In the event of an inadvertent temperature excursion the following data may be used:

Calcium folinate is stable when exposed to a single temperature excursion of <1 month at 25°C. The product can be returned to the fridge with no change to expiry date.

Temperature excursions of 0°C for 7 days will not affect the quality of the product.

Contact Pfizer in cases where additional stability data is required. Refer to the electronic medicines compendium (eMC) at medicines.org.uk for company contact details.