Cenobamate
Published 14th May 2018, updated 17th November 2018
Unassigned
New Medicines
Partial focal epilepsy - adjunctive therapy
Information
New molecular entity
SK Bio-Pharmaceuticals
SK Bio-Pharmaceuticals
Development and Regulatory status
None
Phase III Clinical Trials
Phase III Clinical Trials
Category
A sodium channel blocker, with a binding site different from that of classical sodium channel blocking drugs and it enhances GABAergic transmission by increasing presynaptic GABA release.
Incidence is estimated to be 50 per 100,000 per year and the prevalence of active epilepsy in the UK is estimated to be 5–10 cases per 1000 [1]. ·
Partial focal epilepsy - adjunctive therapy
Oral
Evidence based evaluations
NIHR ·