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Safety in Lactation: Antipsychotics

22 September 2020Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Oral and non-depot antipsychotics with less…

Safety in Lactation: Drugs used in nausea and vertigo

21 September 2020Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. The choice of anti-emetic will depend…

What are the clinically significant drug interactions with tobacco smoking?

23 March 2020This Medicines Q&A summarises those drug interactions with tobacco smoking that are considered to be most clinically important. Most interactions between drugs and tobacco smoking…
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Medicine Compliance Aid Stability

genericDr Reddy's Laboratories (UK) Ltd

Dr Reddy's Laboratories (UK) Ltd
generic
Tablets 25mg, 50mg, 100mg
G2 · Green 2No stability data is available, but manufacturer suggests it is suitable for use in CAs.
Protect from light
Protect from light. Can cause contact dermatitis when handled, wear gloves if handling tablets. Max 14 days in MCA.
1 October 2015

Lactation Safety Information

Oral/standard injection As antipsychotic

Oral/standard injection
As antipsychotic
Haloperidol, Quetiapine
Sedating antipsychotic
Moderate level of published evidence of safety
Long half-life increases risk of accumulation in breastfed infants
Variable levels found in milk which do not appear to correlate with maternal dose or serum level
Drowsiness and lethargy reported in a small number of breastfed infants
Monitor infant for sedation, poor feeding, behavioural effects, extrapyramidal symptoms, and developmental milestones
9 November 2018

As anti-emetic

As anti-emetic
Prochlorperazine
Phenothiazine-like anti-emetic
No published evidence of safety as anti-emetic in breastfeeding, although moderate published evidence as antipsychotic, normally at higher doses
Long half-life increases risk of accumulation in breastfed infants
Drowsiness and lethargy reported in a small number of breastfed infants
Monitor infant for sedation and poor feeding
4 March 2019