Safety in Lactation: Drugs for sleeping disorders

21 October 2020Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Hypnotics Use of hypnotic agents in…
Search Articles

Refrigerated Storage

HeminevrinCheplapharm Arzneimittel GmbH

Cheplapharm Arzneimittel GmbH
Syrup 31.5mg/mL

In the event of an inadvertent temperature excursion the following data may be used:

Discontinuation of the cold chain (6 months at room temperature) of an unopened bottle with subsequent storage in a refrigerator for 18 months has no effect on the specification of the mixture.

After first opening of the container, the syrup can be used 120 days when stored under the specified storage conditions (2°C to 8°C) and 2 months when stored at room temperature (25°C).

If stored below 0°C, the product should be discarded.

Please also refer to the manufacturer’s product literature for recommended storage information at

Yes, as described above
Yes, under the conditions described above

Do not freeze. Protect from light.

Clomethiazole edisilate is known for sorption effects to plastic materials resulting in loss of amounts. Storage in connection with plastic material for application or dilution purposes should be as short as possible.

12 June 2020
London MI Service

Medicine Compliance Aid Stability

genericIntrapharm Laboratories Ltd

Intrapharm Laboratories Ltd
Capsules 192mg
R1 · Red 1Stability data indicates that the drug is not suitable for CAs.
Store in original container. Only store in a glass bottle.
1 October 2015

Lactation Safety Information

Very limited published evidence of safety
Normally only used as a hypnotic in the elderly. Its use as a sedative for drug withdrawal symptoms is normally under specialist supervision
Monitor the infant closely for drowsiness, poor feeding and adequate weight gain
3 January 2018