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Articles

Safety in Lactation: Dopaminergic drugs used in Parkinsons disease

25 September 2020Although rare, Parkinson’s disease can occur in younger women of childbearing age. Dopamine receptor agonists are used either alone or as an adjunct to levodopa…

How do you convert from co-beneldopa (Madopar®) prolonged-release capsules to dispersible tablets?

22 October 2018For patients taking the prolonged-release preparation of co-beneldopa (Madopar® CR), there may be clinical situations when an alternative formulation of co-beneldopa needs to be considered…
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Medicine Compliance Aid Stability

genericTeva UK Ltd

Teva UK Ltd
generic
Capsules 12.5/50, 25/100, 50/200
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Protect from moisture
Complex dosing regime. Protect from moisture. Original pack contains a dessicant. Max 7 days in MCA.
2 November 2015

MadoparRoche Products Ltd

Roche Products Ltd
Madopar
Capsules 62.5mg, 125mg, 250mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Protect from moisture
Complex dosing regime. Protect from moisture. Original pack contains a dessicant. Max 7 days in MCA
2 November 2015

Madopar DispersibleRoche Products Ltd

Roche Products Ltd
Madopar Dispersible
Tablets dispersible 50/12.5 & 100/25
R1 · Red 1Stability data indicates that the drug is not suitable for CAs.
Unsuitable
Dispersible tablet so unsuitable.
2 November 2015

Madopar CRRoche Products Ltd

Roche Products Ltd
Madopar CR
Capsules m/r 125mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Protect from moisture
Complex dosing regime. Protect from moisture. Original pack contains a dessicant. Max 7 days in MCA
2 November 2015

Lactation Safety Information

Benserazide + levodopa

Benserazide + levodopa
Low levels anticipated in milk due to the drug's properties
Limited published evidence of safety of levodopa and no published evidence for benserazide
May interfere with lactation although less likely if lactation established. Monitor milk production
29 July 2020