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Articles

Safety in Lactation: Dopaminergic drugs used in Parkinsons disease

25 September 2020Although rare, Parkinson’s disease can occur in younger women of childbearing age. Dopamine receptor agonists are used either alone or as an adjunct to levodopa…
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Medicine Compliance Aid Stability

genericTeva UK Ltd

Teva UK Ltd
generic
Tablets 10/100, 25/100, 25/250mg
A2 · Amber 2No stability data is available, the manufacturer does not, or cannot recommend use in CAs but there are no theoretical concerns with the product.
No special precautions for storage
No special precautions for storage
26 October 2015

Caramet CRTeva UK Ltd

Teva UK Ltd
Caramet CR
Tablets m/r 25/100, 50/200
A2 · Amber 2No stability data is available, the manufacturer does not, or cannot recommend use in CAs but there are no theoretical concerns with the product.
No special precautions for storage
No special precautions for storage
26 October 2015

SinemetMerck Sharp & Dohme Ltd

Merck Sharp & Dohme Ltd
Sinemet
Tablets 12.5mg/50mg, 10mg/100mg), plus (25/100mg), 275mg (25/250)
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Protect from moisture
Complex dosing regime. Protect from moisture. Max 7 days in MCA
1 March 2013

Half Sinemet CR & Sinemet CRMerck Sharp & Dohme Ltd

Merck Sharp & Dohme Ltd
Half Sinemet CR & Sinemet CR
Tablets m/r 25/100mg, 50/200mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Protect from moisture
Complex dosing regime. Protect from moisture. Max 7 days in MCA
1 March 2013

Lactation Safety Information

Carbidopa + levodopa

Carbidopa + levodopa
Low levels anticipated in milk due to the drug's properties
Limited published evidence of safety of levodopa and no published evidence for carbidopa
May interfere with lactation although less likely if lactation established. Monitor milk production
30 July 2020