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What are the equivalent doses of oral morphine to other oral opioids when used as analgesics in adult palliative care?

9 November 2020Morphine is generally the strong opioid of choice for treating moderate to severe cancer pain and a common question is how to convert a dose…

Safety in Lactation: Opioid analgesics

21 October 2020The evidence relating to the safe use of opioid analgesics in breastfeeding mothers is very variable between individual drugs. This group of drugs presents a…

Can opioids be used for pain relief during pregnancy?

7 May 2020There are no specific guidelines for the treatment of pain in pregnancy. Not all analgesics are suitable for use during or at certain stages of…

Review of high dose opioids in chronic non-malignant pain

12 April 2019The Faculty of Pain Medicine (Royal College of Anaesthetists) states that the morphine dose for which harms outweigh benefits is 120mg oral morphine or equivalent/24…

Which weak opioids can be used during breastfeeding? Considering the evidence for codeine, dihydrocodeine, and tramadol

15 March 2018This updated UKMi Q & A considers the evidence and regulatory recommendations regarding the contraindication of codeine use during breastfeeding. It also considers the evidence…
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Medicine Compliance Aid Stability

genericNon-proprietary

Non-proprietary
generic
Tablets 15mg, 30mg, 60mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Protect from light
Protect from moisture
Store in a dry place and protect from light.
11 May 2015

Lactation Safety Information

For acute diarrhoea

For acute diarrhoea
No
Kaolin, Loperamide
Reports of apnea in breastfed infants. Report of infant death where mother was ultrarapid metaboliser genotype which may lead to increased levels of metabolite, morphine.
European and UK regulatory bodies (EMA/MHRA) have contraindicated the use of codeine in breastfeeding mothers
11 December 2020
Q&A

For cough

For cough
No
Pholcodine, Dextromethorphan
There is no evidence relating to the safety of codeine in breastfeeding when used for cough
Reports of apnea in breastfed infants. Report of infant death where mother was ultrarapid metaboliser genotype which may lead to increased levels of metabolite, morphine
European and UK regulatory bodies (EMA/MHRA) have contraindicated the use of codeine in breastfeeding mothers
11 December 2020

For pain

For pain
No
Dihydrocodeine/ Tramadol, , Ibuprofen/ Diclofenac
Reports of apnea in breastfed infants. Report of infant death where mother was an ultrarapid metaboliser genotype which may lead to increased levels of metabolite, morphine
European and UK regulatory bodies (EMA/MHRA) have contraindicated the use of codeine in breastfeeding mothers
11 December 2020
Q&A