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High dose loperamide use in high stoma output or short bowel syndrome

11 January 2022This guidance explores the dosing and monitoring advice when using high dose loperamide to reduce high stoma output or in short bowel syndrome in adults.

Tool to calculate estimated dose equivalences of oral morphine to other oral opioids

14 September 2021Use our tool to obtain approximate dose equivalences of oral morphine to other oral opioids and help you calculate an estimated equivalent dose

Switching between oral morphine and other oral opioids in adult palliative cancer care patients

14 September 2021Switching between morphine and alternative opioids requires care and thoughtful application of a stepped process

Safety in Lactation: Opioid analgesics

21 October 2020The evidence relating to the safe use of opioid analgesics in breastfeeding mothers is very variable between individual drugs. This group of drugs presents a…

Can opioids be used for pain relief during pregnancy?

7 May 2020There are no specific guidelines for the treatment of pain in pregnancy. Not all analgesics are suitable for use during or at certain stages of…
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Medicine Compliance Aid Stability

genericNon-proprietary

Non-proprietary
generic
Tablets 15mg, 30mg, 60mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Protect from light
Protect from moisture
Store in a dry place and protect from light.
11 May 2015

Lactation Safety Information

For acute diarrhoea

For acute diarrhoea
No
Kaolin, Loperamide
Reports of apnea in breastfed infants. Report of infant death where mother was ultrarapid metaboliser genotype which may lead to increased levels of metabolite, morphine.
European and UK regulatory bodies (EMA/MHRA) have contraindicated the use of codeine in breastfeeding mothers
11 December 2020
Q&A

For cough

For cough
No
Pholcodine, Dextromethorphan
There is no evidence relating to the safety of codeine in breastfeeding when used for cough
Reports of apnea in breastfed infants. Report of infant death where mother was ultrarapid metaboliser genotype which may lead to increased levels of metabolite, morphine
European and UK regulatory bodies (EMA/MHRA) have contraindicated the use of codeine in breastfeeding mothers
11 December 2020

For pain

For pain
No
Paracetamol, Dihydrocodeine/ Tramadol, Ibuprofen/ Diclofenac
Reports of apnea in breastfed infants. Report of infant death where mother was an ultrarapid metaboliser genotype which may lead to increased levels of metabolite, morphine
European and UK regulatory bodies (EMA/MHRA) have contraindicated the use of codeine in breastfeeding mothers
11 December 2020
Q&A