Denosumab
ArticlesRefrigerated StorageLactation Safety InformationNew Medicines · Published , updatedArticles
Safety in Lactation: Drugs affecting bone metabolism
Drugs used exclusively for postmenopausal osteoporosis have not been included. Bisphosphonates have very poor oral bioavailability in fasting adults, which is decreased even further in… Alendronic acid Calcitonin Denosumab Etidronate disodium Risedronate sodiumRefrigerated Storage
ProliaAmgen Ltd
In the event of an inadvertent temperature excursion the following data may be used:
Prolia vials remain stable when exposed to a temporary room temperature exposure up to 30°C. The cumulative room temperature exposure time must not exceed 30 days and exposure should be limited to one to two excursions. In the event of a temporary room temperature exposure, Prolia may be returned to the recommended condition of 2-8°C until the product expiry.
Please also refer to the manufacturer’s product literature for recommended storage information at https://www.medicines.org.uk
Contact Amgen Ltd in cases where additional stability data is required. Refer to the current BNF for company contact details.
XGEVAAmgen Ltd
In the event of an inadvertent temperature excursion the following data may be used:
Xgeva vials remain stable when exposed to a temporary room temperature exposure up to 30°C. The cumulative room temperature exposure time must not exceed 30 days and exposure should be limited to one to two excursions. In the event of a temporary room temperature exposure, Xgeva may be returned to the recommended condition of 2-8°C until the product expiry.
Please also refer to the manufacturer’s product literature for recommended storage information at https://www.medicines.org.uk
Contact Amgen Ltd in cases where additional stability data is required. Refer to the current BNF for company contact details.