Dopamine

Articles · Lactation Safety Information · New Medicines ·

59187003

Articles

Safety in Lactation: Sympathomimetics for acute cardiac conditions

Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Dobutamine, dopamine and dopexamine are inotropes… Adrenaline Cardiovascular system disorders Dobutamine Dopamine Dopexamine Ephedrine Isoprenaline Metaraminol Midodrine Noradrenaline Obstetrics and gynaecology Paediatric and neonatal medicine Phenylephrine Safety in Lactation

Lactation Safety Information

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No published evidence of safety
Low levels anticipated in milk due to very short half-life (2 minutes)
Minimal absorption from the infant’s GI tract
May interfere with lactation, although no clinical evidence to support this
24th February 2017

New Medicines

Hypotension in infants born less than 28 weeks of gestation - ready-to-use formulation

Information

New formulation
BrePco Biopharma

Development and Regulatory status

Phase III Clinical Trials
Phase III Clinical Trials
None

Category

Ready-to-use formulation of dopamine, a sympathomimetic.
Assuming an annual birth rate of 10.25 births per 1,000 population, approximately 25,000 extremely low gestational age newborns (ELGAN) are born every year in the EU. Conservative figures estimate that approximately 12,500 ELGAN per year are hypotensive and receive inotropes [1]
Hypotension in infants born less than 28 weeks of gestation - ready-to-use formulation
Intravenous infusion