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Articles

Safety in Lactation: Drugs for thromboembolic disorders

18 September 2020Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Oral anticoagulants The coumarin anticoagulants, warfarin…

What factors should be considered when using LMWH to treat venous thromboembolism in patients with high body weight?

14 September 2020Treatment of venous thromboembolism (VTE) in patients with high body weight constitutes a challenge in clinical practice. Adjustments in the dose calculation may be necessary…

Low molecular weight heparins – should treatment doses be used in patients with renal impairment?

25 March 2020Randomised controlled trials evaluating LMWH efficacy and safety have generally excluded patients with severe renal impairment (RI). In contrast to UFH, LMWHs are primarily cleared…

Low molecular weight heparins – should prophylactic doses be used in patients with renal impairment?

23 October 2019This updated Medicines Q & A reviews the evidence available and considers when prophylactic doses of low molecular weight heparins can be used in patients…

How should medicines be dosed in children who are obese?

18 October 2018Obesity results in physiological changes that can affect the volume of distribution and the clearance of drugs. The extent of these changes is variable and…
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Lactation Safety Information

Yes
-
Limited published evidence of safety
Low levels anticipated in milk due to the drug’s properties and not absorbed from the infant’s GI tract
Used in full-term neonates from birth
20 October 2016