Eptifibatide

Articles · Refrigerated Storage · Lactation Safety Information ·
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Articles

Safety in Lactation: Drugs for thromboembolic disorders

Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Oral anticoagulants The coumarin anticoagulants, warfarin… Abciximab Acenocoumarol Alteplase Apixaban Argatroban Aspirin Cardiovascular system disorders Clopidogrel Dabigatran etexilate Dalteparin Dipyridamole Edoxaban Enoxaparin Epoprostenol Eptifibatide Fondaparinux Heparin Phenindione Prasugrel Rivaroxaban Safety in Lactation Ticagrelor Tinzaparin Urokinase Warfarin

Refrigerated Storage

Integrilin · GSK

GSK
Integrilin
0.75 mg/mL solution for infusion and 2 mg/mL solution for injection

In the event of an inadvertent temperature excursion the following data may be used:
Eptifibatide solution for infusion 0.75 mg/mL and eptifibatide solution for injection 2 mg/mL are stable when stored for 1 month at 25°C/60% relative humidity.
Please also refer to the manufacturer’s product literature for recommended storage information at https://www.medicines.org.uk.
Contact GSK in cases where the product has been exposed to temperature deviation other than described above. Refer to the current BNF for company contact details.

Information not provided by manufacturer
Information not provided by manufacturer
18th December 2019
London Medicines Information Service

Lactation Safety Information

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Normally administered with aspirin or heparin
No published evidence of safety
Low levels anticipated in milk due to the drug’s properties and likely to be degraded in infant’s GI tract
Consider suspending breastfeeding during eptifibatide infusion to minimise any unknown risks
20th October 2016