Estetrol + drospirenone

Unassigned

New Medicines

Estelle · Contraception

Information

Estelle
New molecular entity
Mithra
Mithra

Development and Regulatory status

None
Phase III Clinical Trials
Phase III Clinical Trials

Category

A fifth generation combined oral contraceptive, composed of estetrol (a natural oestrogen) and drospirenone. In the presence of estradiol acts as an estrogen antagonist. It also favours estrogen receptor (ER)-α; other estrogens favour ER-β.
The last survey on contraceptive use was done by the Office for National Statistics (ONS) in 2008-9 and at that time showed 75% of women aged 16-49 years use some type of contraception, 25% of women use the combined oral contraceptive pill (COCP) and 25% of women rely on male condom use [1].
Contraception
Oral