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Safety in Lactation: Drugs affecting bone metabolism

18 September 2020Drugs used exclusively for postmenopausal osteoporosis have not been included. Bisphosphonates have very poor oral bioavailability in fasting adults, which is decreased even further in…

Can oral bisphosphonates be given to people with renal impairment to treat osteoporosis?

9 July 2020In the main, bisphosphonates are not metabolised and are excreted unchanged in urine. Oral bisphosphonates are licensed for the primary and secondary prevention of osteoporotic…
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Medicine Compliance Aid Stability

DidronelWarner Chilcott UK Ltd

Warner Chilcott UK Ltd
Didronel
Tablets 200mg
R2 · Red 2Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Hygroscopic. Store in airtight containers. Complex administration regime makes it unsuitable for MCA.
29 November 2012

Lactation Safety Information

Yes
No published evidence of safety
Negligible levels anticipated in milk, due to drug’s properties, with subsequent minimal absorption from the infant’s GI tract
10 August 2020