Fentanyl
Articles · Medicine Compliance Aid Stability · Lactation Safety Information · Published , updated
40648001
Articles
19th December 2019
What naloxone doses should be used in adults to urgently reverse the effects of opioids?
The opioid antagonist, naloxone, is a highly effective antidote the use of which is potentially life-saving. The drug has a role in a wide range… Buprenorphine Diamorphine Emergency medicine and urgent care Fentanyl Medicines Safety Methadone Morphine Naloxone Oxycodone Palliative and End of Life Care Pethidine Q&A
30th May 2019
Shortage of Actiq lozenges and Instanyl nasal spray (immediate-release fentanyl citrate)
Actiq lozenges and Instanyl nasal spray are both licensed for the treatment of breakthrough pain in adults with cancer who are already receiving maintenance opioid… Anaesthesia and pain Cancers Fentanyl News Shortages and discontinuations Shortages, Discontinuations and Patent Expiries
20th December 2018
Which opioids can be used in renal impairment?
Opioids are used in a wide variety of clinical settings and are well established for the treatment of both acute and chronic pain. Renal impairment… Alfentanil Anaesthesia and pain Buprenorphine Codeine Diamorphine Dihydrocodeine Fentanyl Hydromorphone Methadone Morphine Oxycodone Pethidine Q&A Renal and urologic disorders Tramadol
19th December 2017
How should conversion from oral morphine to fentanyl patches be carried out?
This updated Medicines Q&A considers the factors which need to be considered when converting patients from oral morphine to fentanyl patches. Explicit guidance on… Fentanyl Medicines Safety Morphine Palliative and End of Life Care Q&A
14th December 2016
What is serotonin syndrome and which medicines cause it?
This Medicines Q&A outlines the causes and symptoms of serotonin syndrome and lists examples of medicines with the potential to cause serotonin syndrome Almotriptan Amitriptyline Bupropion Buspirone Carbamazepine Chlorphenamine Citalopram Clomipramine Dextromethorphan Dosulepin Doxepin Duloxetine Eletriptan Ergotamine Escitalopram Fentanyl Fluoxetine Fluvoxamine Frovatriptan Granisetron Imipramine Isocarboxazid Levodopa Linezolid Lithium Lofepramine Mental Health Methadone Methylthioninium chloride Metoclopramide Mirtazapine Moclobemide Naratriptan Nortriptyline Ondansetron Oxitriptan Oxycodone Paroxetine Pentazocine Pethidine Phenelzine Procarbazine Q&A Rasagiline Rizatriptan Selegiline Sertraline Sodium valproate St. John's wort Sumatriptan Tapentadol Tramadol Tranylcypromine Trazodone Trimipramine Tryptophan Venlafaxine Zolmitriptan
20th May 2012
Safety in Lactation: Opioid analgesics
The evidence relating to the safe use of opioid analgesics in breastfeeding mothers is very variable between individual drugs. This group of drugs presents a… Buprenorphine Codeine Diamorphine Dihydrocodeine Dipipanone + Cyclizine Fentanyl Hydromorphone Meptazinol Methadone Morphine Oxycodone Papaveretum Pentazocine Pethidine Tapentadol Tramadol
20th May 2012
Safety in Lactation: Sedative and analgesic peri-operative drugs
Benzodiazepines are used for premedication and for conscious sedation during surgery. Following short–term therapy (1-2 doses) for these indications, it is considered that breastfeeding can… Alfentanil Dexmedetomidine Diazepam Fentanyl Ketorolac Lorazepam Midazolam Parecoxib Remifentanil TemazepamMedicine Compliance Aid Stability
Abstral · ProStrakan Pharmaceuticals
ProStrakan Pharmaceuticals
Abstral
Tablets sublingual - various strengths
R2 · Red 2 · Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Designed for sublingual administration
11th May 2015
Effentora · Cephalon UK Ltd
Cephalon UK Ltd
Effentora
Buccal tablets - various strengths
R2 · Red 2 · Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Unsuitable for MCA as hygroscopic buccal tablets designed for sublingual administration.
11th May 2015
Actiq · Flynn Pharma Ltd
Flynn Pharma Ltd
Actiq
Lozenge (buccal) - various strengths
R2 · Red 2 · Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Unsuitable for MCA as hygroscopic buccal tablets, which should not be swallowed.
11th May 2015
Lactation Safety Information
Tablets / Lozenges / Nasal spray / Transdermal for pain
Tablets / Lozenges / Nasal spray / Transdermal
for pain
Small amounts in breast milk probably due to short half-life
Although adverse effects in infant are not likely, infant monitoring advised, especially in young infants (see summary)
Injection for use during surgery
Injection
for use during surgery
Small amounts in breast milk probably due to short half-life