dm+d
96220002
Articles
Safety in Lactation: Antidepressants
21 October 2020Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Monamine-oxidase inhibitors (MAOIs) Due to the…
Safety in Lactation: Antipsychotics
22 September 2020Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Oral and non-depot antipsychotics with less…
Lactation Safety Information
For depression
For depression
TCA: imipramine/nortriptyline SSRI: paroxetine/sertraline
Very limited published evidence of safety
Small amounts in breast milk due to high protein binding and high volume of distribution, but long half-life increases risk of accumulation in breastfed infants
Maternal oral doses of up to 4 mg daily produce low levels in milk
Monitor infant for drowsiness, poor feeding, irritability, and behavioural effects
23 September 2020
Oral as antipsychotic
Oral
as antipsychotic
Haloperidol, Quetiapine
Very limited published evidence of safety
Maternal oral doses of up to 4 mg daily produce small amounts in breast milk due to high protein binding and high volume of distribution, but long half-life increases risk of accumulation in breastfed infants
Monitor infant for drowsiness, poor feeding, irritability, and behavioural effects
23 September 2020
Depot injection
Depot injection
see entry under Flupentixol decanoate
23 September 2020