Safety in Lactation: Drugs used for allergic conditions

22 May 2017Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Antihistamines Non-sedating antihistamines (NSA) are preferred…
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Medicine Compliance Aid Stability

GrazaxALK-Abello Ltd

ALK-Abello Ltd
Tablet 75,000units
R2 · Red 2Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Very sensitive to moisture.
29 September 2015

Lactation Safety Information

No published evidence of safety
Components of the allergen unlikely to enter breast milk
If possible, delay desensitisation therapy until no longer breastfeeding
No adverse effects reported in breastfed infants
9 September 2021

New Medicines

Moderate to severe grass pollen-induced seasonal allergic rhinoconjunctivitis in adults


New molecular entity
ASIT Biotech
ASIT Biotech

Development and Regulatory status

Phase III Clinical Trials


A peptide hydrolysate from Lolium perenne, consisting of highly purified natural allergen fragments. The ASIT+ allergen fragments rapidly triggers a protective immune response without need of an adjuvant. Given as 4 doses over 3 weeks.
Allergic rhinitis is a common problem, affecting over 20% of the UK population. Grass pollens usually cause symptoms from late spring to early summer. Main lines of treatment are education, allergy avoidance, antihistamines and topical steroids [1]. NHS England has estimated that ~20,000 people in England require referral to a specialist centre for severe allergy, with half of those receiving specialist interventions such as immunotherapy or investigation for drug allergy [2].
Moderate to severe grass pollen-induced seasonal allergic rhinoconjunctivitis in adults
Subcutaneous injection