In the event of an inadvertent temperature excursion the following data may be used:
The vaccine components are stable at temperatures up to 37°C for a cumulative time of 168 hours.
Temperature excursions down to -20°C do not impact the quality of the product.
The product can be returned to the fridge and no change in expiry dates is required if exposed to the above conditions.
Contact GSK in cases where additional stability data is required. Refer to the electronic medicines compendium (eMC) at https://www.medicines.org.uk for company contact details.
Public Health England has guidance on responding to errors in vaccine storage, handling and administration.