Insulin human





Using antidiabetic medicines during breastfeeding

2 February 2023Insulin or metformin are the preferred choices during breastfeeding. Recommendations apply to full term and healthy infants only.
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Refrigerated Storage

Insuman Basal, Insuman Rapid, Insuman Infusat, Insuman CombSanofi

Insuman Basal, Insuman Rapid, Insuman Infusat, Insuman Comb
Solution for injection 100 units/mL. Vials, cartridges and pre-filled disposable injection devices (Solostar)

In the event of an inadvertent temperature excursion the following data may be used:
For Insuman Infusat: The product (cartridges in-use in the pump) may be stored for a maximum of 2 weeks. The manufacturer states that once opened and attached to the pump, the storage conditions for the Insuman Infusat should comply with the ambient temperature of the pump.
The SPC and manufacturer do not specify the temperature range at which the Insuman Infusat should be stored at whilst within the pump, this will ultimately be a clinical decision made at the discretion of the treating healthcare professional.

For all other Insuman preparations: Once Insuman is taken out of the refrigerator for the first time, it can be kept for 28 days at temperatures of up to 25°C away from direct heat or direct light. Do not use Insuman if the storage temperature has exceeded 25°C.
Once a new pen or cartridge has been started, it is recommended to store the insulin pen at room temperature and not to put it back in the refrigerator, as the cold temperature may affect the mechanics of the pen and it may become difficult to use. The pen cap must be put back on the pen after each injection in order to protect from light.

Please also refer to the manufacturer’s product literature for recommended storage information at

Reduce the expiry date to 28 days if the storage temperature has not exceeded 25°C.
3 November 2022
London MI Service