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Using antidiabetic medicines during breastfeeding

2 February 2023Insulin or metformin are the preferred choices during breastfeeding. Recommendations apply to full term and healthy infants only.
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Refrigerated Storage

Human InsulatardNovo Nordisk

Novo Nordisk
Human Insulatard
Injections (vials, Penfills, Innolet, FlexPen)

In the event of an inadvertent temperature excursion the following data may be used:
Insulatard vial: The products are stable when exposed to temperatures <25°C for 4 weeks (40units/mL) or 6 weeks (100units/mL).
Insulatard Penfill, InnoLet, FlexPen: The products are stable when exposed to temperatures <30°C for 6 weeks.

Please refer to the manufacturer’s product literature for recommended storage information at https://www.medicines.org.uk

Reduce expiry to 4 weeks or 6 weeks depending on the formulation as described above
If exposed to the conditions above, keep the product outside of the fridge.
20 January 2022
London MI Service

Humulin IEli Lilly

Eli Lilly
Humulin I
100units/mL suspension for injection in pre-filled Kwikpen, cartridge and vial

In the event of an inadvertent temperature excursion the following data may be used:
The cartridge, pre-filled pens and vials are stable when exposed to temperatures below 30°C for 28 days.
Contact Eli Lilly in all other cases where a deviation from the recommended storage conditions has occurred. Refer to the electronic medicines compendium (eMC) at https://www.medicines.org.uk for company contact details and product literature.

Yes - reduce expiry to 28 days if exposed to the conditions above
No - store the products outside of the fridge if exposed to the conditions above
22 March 2023
London MI Service