Insulin preparations: RMOC recommendations of safety considerations for formulary decision making

22 June 2018At its meeting on 18th April 2018 the Regional Medicines Optimisation Committee (RMOC) (Midlands and East) reviewed issues pertaining to safety considerations when adopting any…
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Refrigerated Storage

Humalog Mix25, Humalog Mix50Eli Lilly

Eli Lilly
Humalog Mix25, Humalog Mix50
100 units/ml suspension for injection in vial, cartridge, pre-filled pen

In the event of an inadvertent temperature excursion the following data may be used:
The cartridge and pre-filled pens are stable when exposed to temperatures <30°C for 28 days. Do not return to the fridge.
The vials are stable when exposed to temperatures <30°C for 28 days. Following the excursion, the vials can be returned to the fridge or stored outside of the fridge (<30°C).
Please also refer to the manufacturer’s product literature for recommended storage information at

Contact Eli Lilly in all other cases where a deviation from the recommended storage conditions has occurred. Refer to the current BNF for company details.

Reduce to 28 days if exposed to the conditions above
Store cartridges and pre-filled pens outside of the fridge if exposed to the conditions above
29 September 2021
London MI Service