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Insulin preparations: RMOC recommendations of safety considerations for formulary decision making

22 June 2018At its meeting on 18th April 2018 the Regional Medicines Optimisation Committee (RMOC) (Midlands and East) reviewed issues pertaining to safety considerations when adopting any…
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Refrigerated Storage

Human ActrapidNovo Nordisk

Novo Nordisk
Human Actrapid
Injection (vials, Penfills, InnoLet, FlexPen)

In the event of an inadvertent temperature excursion the following data may be used:
Actrapid vial: The products are stable when exposed to temperatures <25°C for 4 weeks (40 units/mL) or 6 weeks (100 units/mL).
Actrapid Penfill, InnoLet, FlexPen: The products are stable when exposed to temperatures <30°C for 6 weeks.

Please refer to the manufacturer’s product literature for recommended storage information at https://www.medicines.org.uk

Reduce expiry to the duration as specified above
If exposed to the conditions above, keep the product outside of the fridge
20 January 2022
London MI Service

Humulin SEli Lilly

Eli Lilly
Humulin S
100 units/ml solution for injection vial and cartridge

In the event of an inadvertent temperature excursion the following data may be used:
The cartridges are stable when exposed to temperatures <30°C for 28 days. Do not return to the fridge.
The vials are stable when exposed to temperatures <30°C for 28 days.
Please also refer to the manufacturer’s product literature for recommended storage information at https://www.medicines.org.uk

Contact Eli Lilly in all other cases where a deviation from the recommended storage conditions has occurred. Refer to the current BNF for company details.

Reduce expiry to 28 days if exposed to the conditions above
The cartridges can be stored outside of the fridge if exposed to the conditions above
29 September 2021
London MI Service