Lamotrigine
ArticlesMedicine Compliance Aid StabilityLactation Safety Information · Published , updated
96195007
Articles
21 September 2020
Safety in Lactation: Control of epilepsy
Choice will depend on clinical condition, and should primarily be based on suitability for the patient, rather than safety during breastfeeding. Whilst sodium valproate is… Carbamazepine Clobazam Clonazepam Ethosuximide Gabapentin Lacosamide Lamotrigine Levetiracetam Oxcarbazepine Perampanel Phenobarbital Phenytoin Pregabalin Primidone Sodium valproate Topiramate ZonisamideMedicine Compliance Aid Stability
genericNon-proprietary
Non-proprietary
generic
Tablets 25mg, 50mg, 100mg, 200mg,
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Store in airtight containers.
23 February 2015
LamictalGlaxoSmithKline UK
GlaxoSmithKline UK
Lamictal
Tablets dispersible 2mg, 5mg, 25mg, 100mg
R2 · Red 2Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Unsuitable for MCA as dispersible tablets.
23 February 2015
genericNon-proprietary
Non-proprietary
generic
Tablets dispersible 5mg, 25mg, 100mg
R2 · Red 2Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Unsuitable.
23 February 2015
LamictalGlaxoSmithKline UK
GlaxoSmithKline UK
Lamictal
Tablets 25mg, 50mg, 100mg, 200mg,
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
No special requrements for storage
23 February 2015
Lactation Safety Information
For epilepsy
For epilepsy
Suitable alternative antiepileptic
Significant published evidence of use in breastfeeding
Significant amounts in breast milk
Long half-life increases risk of accumulation in breastfed infants
Mild thrombocytosis reported in some infants. Single case reports of severe apnoea, reversible anaemia and neutropenia in breastfed infants possibly associated with lamotrigine
Monitor infant for rash, apnoea, drowsiness and poor feeding. If rash occurs breastfeeding should be withheld until the cause can be established.
9 January 2020