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Safety in Lactation: Control of epilepsy
21 September 2020Choice will depend on clinical condition, and should primarily be based on suitability for the patient, rather than safety during breastfeeding. Whilst sodium valproate is…
Lactation Safety Information
For epilepsy
For epilepsy
Suitable alternative antiepileptic
Significant published evidence of use in breastfeeding
Significant amounts in breast milk
Long half-life increases risk of accumulation in breastfed infants
Mild thrombocytosis reported in some infants. Single case reports of severe apnoea, reversible anaemia and neutropenia in breastfed infants possibly associated with lamotrigine
Monitor infant for rash, apnoea, drowsiness and poor feeding. If rash occurs breastfeeding should be withheld until the cause can be established.
9 January 2020