X-ALD results in cerebral demyelination, axonal dysfunction in the spinal cord leading to spastic paraplegia, adrenal insufficiency & sometimes testicular insufficiency. X-ALD is the most common peroxisomal disorder with an estimated birth incidence of 1/20,000 (male & female). Male hemizygotes may present with neurological symptoms in 2 forms: X-linked cerebral adrenoleukodystrophy (X-CALD) & adrenomyeloneuropathy (AMN). AMN is characterised by the onset of spastic paraplegia in adult men [1].