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Articles

Safety in Lactation: Drugs for cytotoxic-induced side-effects

25 September 2020As these drugs are used to prevent, or treat, specific adverse effects of certain antineoplastic agents or radiotherapy, the risk of their use in breastfeeding…
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Refrigerated Storage

IsovorinPfizer

Pfizer
Isovorin
Solution for Injection 10 mg/mL

Contact Pfizer in all cases where a deviation from the recommended storage conditions has occurred. Refer to the electronic medicines compendium (eMC) at https://www.medicines.org.uk for company contact details.

10 March 2022
London MI Service

Levofolinic acidMedac GmbH

Medac GmbH
Levofolinic acid
50mg/mL solution for injection or infusion

In the event of an inadvertent temperature excursion the following data may be used:
In-house stability data supports a temperature excursion of up to 72 hours to a maximum temperature of 25°C.
Please also refer to the manufacturer’s product literature for recommended storage information at https://www.medicines.org.uk

3 February 2022
London MI Service

Lactation Safety Information

Calcium/ disodium levofolinate

Calcium/ disodium levofolinate
Yes
No published evidence of safety
Isomer of folinic acid used to reduce toxicity of methotrexate and as an adjunct to fluorouracil
Folic acid is a normal component of breast milk
16 September 2020