Safety in Lactation: Drugs for cytotoxic-induced side-effects

25 September 2020As these drugs are used to prevent, or treat, specific adverse effects of certain antineoplastic agents or radiotherapy, the risk of their use in breastfeeding…
Search Articles

Refrigerated Storage


Solution for Injection 10 mg/mL

Contact Pfizer in all cases where a deviation from the recommended storage conditions has occurred. Refer to the electronic medicines compendium (eMC) at for company contact details.

10 March 2022
London MI Service

Levofolinic acidMedac GmbH

Medac GmbH
Levofolinic acid
50mg/mL solution for injection or infusion

In the event of an inadvertent temperature excursion the following data may be used:
In-house stability data supports a temperature excursion of up to 72 hours to a maximum temperature of 25°C.
Please also refer to the manufacturer’s product literature for recommended storage information at

3 February 2022
London MI Service

Lactation Safety Information

Calcium/ disodium levofolinate

Calcium/ disodium levofolinate
No published evidence of safety
Isomer of folinic acid used to reduce toxicity of methotrexate and as an adjunct to fluorouracil
Folic acid is a normal component of breast milk
16 September 2020