Lorazepam
ArticlesRefrigerated StorageMedicine Compliance Aid StabilityLactation Safety Information · Published , updatedArticles
Equivalent doses of oral benzodiazepines
Benzodiazepines are the most commonly used anxiolytics and hypnotics. There are major differences in potency between different benzodiazepines and this difference in potency is important… Alprazolam Chlordiazepoxide Clobazam Clonazepam Diazepam Dosing Flurazepam Loprazolam Lorazepam Lormetazepam Mental Health Mental health and illness Nitrazepam Oxazepam Switching TemazepamSafety in Lactation: Drugs used in status epilepticus
Choice of treatment will be influenced by the clinical situation. The evidence for these drugs in breastfeeding is based on their longer-term use rather than… Clonazepam Diazepam Fosphenytoin Lorazepam Midazolam Phenobarbital sodium Phenytoin sodiumSafety in Lactation: Anxiolytics.
Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Use of anxiolytics in breastfeeding mothers… Alprazolam Buspirone Chlordiazepoxide Diazepam Lorazepam Mental health and illness Obstetrics and gynaecology Oxazepam Paediatrics and neonates Safety in BreastfeedingSafety in Lactation: Sedative and analgesic peri-operative drugs
Benzodiazepines are used for premedication and for conscious sedation during surgery. Following short–term therapy (1-2 doses) for these indications, it is considered that breastfeeding can… Alfentanil Dexmedetomidine Diazepam Fentanyl Lorazepam Midazolam TemazepamLorazepam products: ambient stability during COVID-19
This page gives ambient stability information for Lorazepam products during COVID-19. Information here should be used in conjunction with our general advice. Lorazepam 4mg/1ml solution… COVID-19 Medicines Optimisation: Information and resources Lorazepam Stability outside the fridgeShortage of Ativan (lorazepam) Injection 4 mg in 1 ml
Supplies will be extremely limited between week commencing 5th October until early December 2020 and reserved for primary care only. Pfizer is supplying an alternative… Anaesthesia and pain Lorazepam Mental Health Neurological disorders SupplyRefrigerated Storage
AtivanPfizer Ltd
Contact Pfizer Limited in all cases where a deviation from the recommended storage conditions has occurred. Refer to the current BNF for company contact details.
Please also refer to the manufacturer’s product literature for recommended storage information at https://www.medicines.org.uk
During the COVID emergency it is especially important to conserve medicine stocks and to minimise avoidable waste. If ANY critical medicines are subject to temperature excursions during this time and your pharmacy team are in any doubt about whether or not it is safe to use them, you are strongly advised to contact your Regional QA Pharmacist to agree the most appropriate course of action.
CarpujectPfizer Ltd
In the event of an inadvertent temperature excursion the following data from the manufacturer can be considered:
An unpublished in-house stability study suggests that product quality may be maintained when exposed to temperatures not exceeding 25°C for up to a period of 1 month.
However it is important to note that it is not possible to verify these data and healthcare professionals need to make their own practical decisions about its use in each situation, seeking input from colleagues with quality assurance expertise if needed.
The manufacturer (Pfizer Limited) can also be contacted for further clarification in all cases where a deviation from the recommended storage conditions has occurred. Refer to the current BNF for company contact details.
During the COVID emergency it is especially important to conserve medicine stocks and to minimise avoidable waste. If ANY critical medicines are subject to temperature excursions during this time and your pharmacy team are in any doubt about whether or not it is safe to use them, you are strongly advised to contact your Regional QA Pharmacist to agree the most appropriate course of action.