dm+d

Unassigned

New Medicines

Blepharitis caused by Demodex mites

Information

New molecular entity
Tarsus Pharmaceuticals
Tarsus Pharmaceuticals

Development and Regulatory status

None
None
Phase III Clinical Trials

Category

Lotilaner can paralyse and eradicate mites and other parasites through the inhibition of parasite-specific GABA-chloride channels, acting as the GABAA receptor antagonist. This 0.25% ophthalmic solution is designed to target and eradicate Demodex mites.
Blepharitis accounts for at least 5% of ophthalmological presentations in primary care. Blepharitis is caused by staphylococcal infection, seborrhoeic dermatitis, meibomian gland dysfunction, Demodex mites or any combination of these factors [1]
Blepharitis caused by Demodex mites
Topical