Maraviroc
Articles · Medicine Compliance Aid Stability · Lactation Safety Information · New Medicines · Published , updated
427805000
Articles
20th May 2012
Safety in Lactation: HIV infection
Breastfeeding by HIV-positive mothers may cause HIV infection in the infant and should be avoided where possible. The use of HIV drugs during breastfeeding is… Abacavir Atazanavir Darunavir Didanosine Efavirenz Emtricitabine Enfuvirtide Etravirine Fosamprenavir Indinavir Lamivudine Lopinavir + Ritonavir Maraviroc Nelfinavir Nevirapine Raltegravir Rilpivirine Ritonavir Saquinavir Stavudine Tenofovir Tenofovir disoproxil Tipranavir ZidovudineMedicine Compliance Aid Stability
Celsentri · ViiV Healthcare UK Ltd
ViiV Healthcare UK Ltd
Celsentri
Tablets 150mg 300mg
A2 · Amber 2 · No stability data is available, the manufacturer does not, or cannot recommend use in CAs but there are no theoretical concerns with the product.
No special precautions for storage
Does not require any special storage conditions
17th August 2015
Lactation Safety Information
Specialist drug/complex disease area for which expert advice is recommended
New Medicines
Celsentri (outside US), Selzentry (US) · HIV infection with only CCR5-tropic HIV-1 detectable in treatment-experienced adolescents and children of 2 years of age and older and weighing at least 10 kg - in combination with other antiretroviral medicinal products
Information
Celsentri (outside US), Selzentry (US)
Licence extension / variation and new formulation
ViiV Healthcare
ViiV Healthcare
Development and Regulatory status
Launched
Launched
None
December 2017
Dec 17: Launched in UK. Price 20mg/ml sugar-free oral soln, 230ml=£230.44 [5].
Jul 17: The SPC is available on the EMC;[3] however, the oral solution is not expected to be available until November this year due to manufacturing delays [4].
Apr 17: EU positive opinion for a licence change for use in adolescents and children of 2 years of age and older and weighing at least 10 kg [1].
Category
A chemokine receptor 5 (CCR5) antagonist
In 2005, the estimated vertical transmission rate in infants born in the UK to women infected with HIV was less than 4%. 120 children aged under 16 years were diagnosed as HIV-positive [2].
HIV infection with only CCR5-tropic HIV-1 detectable in treatment-experienced adolescents and children of 2 years of age and older and weighing at least 10 kg - in combination with other antiretroviral medicinal products
Oral