Methadone

51758009

Articles

Medicine Compliance Aid Stability

generic · Non-proprietary

Non-proprietary
generic
Tablets 5mg
A3 · Amber 3 · No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Protect from light
Protect from moisture
Keep dry and protect from light.
11th May 2015

Lactation Safety Information

For pain

For pain
Morphine or other appropriate analgesic
Small amounts in breast milk
Infant monitoring advised, especially in young infants (see summary)
Although considered compatible with breastfeeding, the use of methadone is limited mainly to treatment of opioid dependence. See more extensive comments under this use of methadone – 4.10.3

For opioid dependence

For opioid dependence
Small amounts in breast milk
Moderate level of evidence and experience of use in breastfeeding
Infants exposed to methadone in utero should breastfeed normally after delivery if mother is stable
Methadone in breast milk may decrease withdrawal symptoms if infant exposed in utero, but will be insufficient to allow dose reduction of any treatment of the infant
Infants may experience withdrawal symptoms if the mother has an abrupt withdrawal of methadone or if the infant is weaned abruptly
Adverse effects more likely to occur in infants not exposed in utero or when the mother is receiving a high maintenance dose
Infant monitoring advised, especially in young infants (see summary)