Methoxyflurane

31363511000001101

New Medicines

Penthrox · Acute pain in children aged 6 to 17 years

Information

Penthrox
Licence extension / variation
Galen
Medical Developments International

Development and Regulatory status

Phase III Clinical Trials
None
None

Category

General inhalation anesthetic that induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling.
In a 12-month study assessing prevalence of acute pain (regardless of cause) in 6,371 children attending emergency departments (EDs) in Ireland by ambulance, 2,635 (41%) has pain documented as their primary symptom. Of these children, 689 (26%) children received an analgesic agent prior to ED arrival and 1,324 (50%) children had an analgesic agent administered on arrival at ED [1].
Acute pain in children aged 6 to 17 years
Inhalation