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Articles

Metronidazole for treatment of Bacterial vaginosis and trichomonas vaginalis: PGD template

5 October 2021A PGD template developed by SPS and the British Association of Sexual Health and HIV (BASHH) and British Association of HIV (BHIVA).

Switching between liquid and tablet/capsule formulations - Which medicines require extra care?

19 July 2021For a small number of medicines, there are differences in equivalent doses of oral formulations of the same medicine. This needs to be considered when…

How should medicines be dosed in children who are obese?

28 May 2021Review on how to calculate medicine doses in children who are obese which includes a table on commonly prescribed medicines.

Metronidazole – is it safe to use with breastfeeding?

12 October 2020The balance of current evidence and clinical experience, and the consensus of specialist opinion, is that there is no established mutagenic or carcinogenic risk to…
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Medicine Compliance Aid Stability

genericAurobindo Pharma-Milpharm Ltd

Aurobindo Pharma-Milpharm Ltd
generic
Tablets 200mg, 400mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Protect from moisture
Protect from moisture
6 July 2015

FlagylZentiva

Zentiva
Flagyl
Tablets 200mg, 400mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Protect from light
Airtight container. Protect from light
6 July 2015

Lactation Safety Information

Intravenous / Oral / Suppositories

Intravenous / Oral / Suppositories
Evidence shows moderate levels in breast milk and infant serum; infant serum levels far less than those when used therapeutically in infants
Only minor gastro-intestinal disturbances reported
No interruption of breastfeeding required, even after 2g oral doses
Monitor infant for gastro-intestinal disturbances and oral candida infection, especially if used in high doses, although these effects are unlikely to occur
Seek specialist advice if use required for longer than a few weeks
22 October 2021
Q&A

For topical use including intravaginal gel

For topical use including intravaginal gel
Yes
Although there is no direct evidence for topical/intravaginal use during breastfeeding, maternal systemic absorption is minimal and therefore milk levels will be negligible
When applying creams/gel, ensure the baby does not come into contact with the areas of the body it is applied to. Wash hands thoroughly after application
22 October 2021
Q&A