Mirtazapine to other antidepressants: switching in adults

17 February 2023Suggested methods for switching safely from mirtazapine to other antidepressants. Switches requiring additional specialist support are highlighted.

Choosing an antidepressant for people with coronary heart disease

2 July 2021Making a suitable choice of antidepressant in CHD needs to include considerations of both the patient and the characteristics of the medicines.

Safety in Lactation: Antidepressants

21 October 2020Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Monamine-oxidase inhibitors (MAOIs) Due to the…

What is serotonin syndrome and which medicines cause it?

22 May 2020This Medicines Q&A outlines the causes and symptoms of serotonin syndrome and provides examples of medicines with the potential to cause serotonin syndrome.  
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Lactation Safety Information

TCA: imipramine/nortriptyline SSRI: paroxetine/sertraline
Limited published evidence of safety
Small amounts in breast milk but long half-life increases risk of accumulation in breastfed infants
Monitor infant for drowsiness, poor feeding, irritability/behavioural effects
22 January 2020