Nabiximols

Articles · New Medicines ·
10599511000001109

Articles

New Medicines

Sativex · Cerebral palsy or traumatic CNS injury-related spasticity in children

Information

Sativex
Licence extension / variation
GW Pharmaceuticals
GW Pharmaceuticals

Development and Regulatory status

Discontinued
Discontinued
Discontinued
Jul 19 · Not listed in GW Pharma pipeline, or latest investor presentation, or latest annual report. No results posted for PIII study completed in 2017. Assume development discontinued [5].

Category

Consists of 2 cannabinoids -CBD (cannabidiol) and THC (delta 9 tetrahydrocannabinol) - binds to cannabinoid receptors
Abnormalities of tone, including hypotonia (floppiness), spasticity (stiffness) or dystonia (fluctuating tone) are possible early motor features in the presentation of cerebral palsy. Pooled data from five active cerebral palsy registers in the UK suggest a mean annual prevalence rate for normal birth-weight children of 1.2 per 1,000 live births [1].
Cerebral palsy or traumatic CNS injury-related spasticity in children
Oral