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Suggestions for Therapeutic Drug Monitoring in Adults in Primary Care

29 September 2020This document is intended to support local discussions on how to monitor commonly prescribed high risk medicines in primary care.    The monitoring parameters cited…

Safety in Lactation: Non-steroidal anti-inflammatory drugs

23 September 2020There is very limited information on the use of NSAIDs during breastfeeding; ibuprofen and diclofenac are the preferred choices due to their extensive safe use…

Do NSAIDs increase the risk of severe skin reactions in children with chickenpox?

1 October 2019This Q&A evaluates the limited published evidence investigating an association between Non-steroidal anti-inflammatory drugs (NSAIDs) and severe skin reactions in children with chickenpox.
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Medicine Compliance Aid Stability

genericActavis UK Ltd

Actavis UK Ltd
generic
Tablets 250mg, 375mg, 500mg
A1 · Amber 1Stability data is available in an alternative container (not CAs) that may be extrapolated to support storage in CAs.
Airtight container
Protect from light
Protect from light. Store in well-closed containers.
29 January 2015

NaprosynRoche Products Ltd

Roche Products Ltd
Naprosyn
Tablets 250mg, 500mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Protect from light
Airtight and light resistant container.
29 January 2015

Naprosyn ECRoche Products Ltd

Roche Products Ltd
Naprosyn EC
Tablets e/c 250mg, 375mg, 500mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Protect from light
Airtight and light resistant container.
29 January 2015

Lactation Safety Information

Ibuprofen, Diclofenac
Long half-life increases risk of accumulation in breastfed infants
Small amounts in breast milk
Very limited published evidence of safety
Case reports of possible adverse effects in infants due to naproxen in breast milk include: prolonged bleeding, thrombocytopenia, acute anaemia, hypovolaemic shock, drowsiness and vomiting, although a causal link was not confirmed in any case
Considered safe for short-term use
22 September 2020