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How do you convert an oral pyridostigmine or neostigmine dose to a parenteral neostigmine dose?

23 April 2020This updated Medicines Q&A gives suggested dose conversions from oral pyridostigmine or neostigmine to parenteral neostigmine and includes example dose conversion calculations
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Medicine Compliance Aid Stability

genericAlliance Pharmaceuticals

Alliance Pharmaceuticals
generic
Tablets 15mg
R2 · Red 2Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Product is hygroscopic, need to protect from light and moisture.
14 January 2015

Lactation Safety Information

For neuromuscular blockade

For neuromuscular blockade
Yes
No published evidence of safety
Negligible levels anticipated in milk due to the drug’s properties
Breastfeeding can resume as soon as the mother has recovered from the effects of general anaesthesia
30 October 2020

For myasthenia gravis

For myasthenia gravis
Yes
Pyridostigmine
No useful published evidence of safety
Negligible levels anticipated in milk due to the drug’s properties
7 August 2020