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Safety in Lactation: Drugs for hypertension

23 September 2020Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Many of the drugs covered by…

What are the reported incidences of ankle oedema with different calcium channel blockers?

1 June 2020The potential to cause ankle oedema appears to exist for all calcium channel blocking agents, and is caused by increasing capillary pressure leading to leakage…

How should ankle oedema caused by calcium channel blockers be treated?

1 June 2020Ankle oedema is a common, often troublesome adverse effect for patients who are receiving calcium channel blocker (CCB) therapy, and may affect compliance. It is…
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Medicine Compliance Aid Stability

Cardene SRAstellas Pharma Ltd

Astellas Pharma Ltd
Cardene SR
Capsules m/r 30mg, 45mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Protect from light
Protect from moisture
Nicardipine is light sensitive and so must be protected from light and excessive humidity.
9 November 2015

CardeneAstellas Pharma Ltd

Astellas Pharma Ltd
Cardene
Capsules 20mg, 30mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Protect from light
Protect from moisture
Protect from light and moisture.
9 November 2015

Lactation Safety Information

Yes
-
Moderate published evidence of safety
Small amounts in breast milk
Used in full-term neonates from birth
16 January 2017