Safety in Lactation: Antipsychotics

22 September 2020Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Oral and non-depot antipsychotics with less…
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Lactation Safety Information

Depot injection

Depot injection
Very limited published evidence of safety indicates only negligible amounts in breast milk following depot injection. However maternal oral doses of up to 20mg daily produce low levels in milk and undetectable levels in infant’s plasma
Long half-life increases risk of accumulation in breastfed infants
Occasional adverse effects reported including somnolence, lethargy poor sucking, irritability and tremor
Monitor infant for sedation, poor feeding, behavioural effects, extrapyramidal symptoms, and developmental milestones
13 August 2020