Olanzapine embonate
ArticlesLactation Safety Information · Published , updated
17067211000001109
Articles
22 September 2020
Safety in Lactation: Antipsychotics
Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Oral and non-depot antipsychotics with less… Amisulpride Aripiprazole Benperidol Chlorpromazine Clozapine Flupentixol Flupentixol decanoate Fluphenazine decanoate Haloperidol Haloperidol decanoate Levomepromazine Loxapine Lurasidone Mental health and illness Obstetrics and gynaecology Olanzapine Olanzapine embonate Paediatrics and neonates Paliperidone Pericyazine Perphenazine Pipotiazine Promazine Quetiapine Risperidone Safety in Breastfeeding Sulpiride Trifluoperazine Zuclopenthixol Zuclopenthixol decanoateLactation Safety Information
Depot injection
Depot injection
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Very limited published evidence of safety indicates only negligible amounts in breast milk following depot injection. However maternal oral doses of up to 20mg daily produce low levels in milk and undetectable levels in infant’s plasma
Long half-life increases risk of accumulation in breastfed infants
Occasional adverse effects reported including somnolence, lethargy poor sucking, irritability and tremor
Monitor infant for sedation, poor feeding, behavioural effects, extrapyramidal symptoms, and developmental milestones
13 August 2020