Ondansetron
ArticlesMedicine Compliance Aid StabilityLactation Safety InformationNew Medicines · Published , updated
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Articles
6 November 2020
What injections can be given orally or via enteral feeding tubes?
This updated Medicines Q&A is a quick reference summary to different types of enteral feeding tubes, in relation to medication issues. Not all enteral feeding… Acetazolamide Acetylcysteine Aminophylline Amoxicillin Arginine Atropine Benzatropine Calcium folinate Chlorphenamine Clonazepam Clonidine Cyclizine Cyclophosphamide Desferrioxamine Dexamethasone Diazepam Digoxin Dinoprostone Dipyridamole Disopyramide Flecainide Flucloxacillin Glycopyrronium Hydralazine Hydrocortisone Hyoscine butylbromide Hyoscine hydrobromide Ketamine Labetalol Levomepromazine Medicines Safety Medroxyprogesterone Methotrexate Methylprednisolone sodium succinate Metoclopramide Metoprolol Midazolam Mycophenolate mofetil Ondansetron Pentazocine Pethidine Phytomenadione Procainamide Procyclidine Propranolol Ranitidine Sodium bicarbonate Sodium chloride Sodium phenylbutyrate Tranexamic acid Vancomycin Verapamil
21 September 2020
Safety in Lactation: Drugs used in nausea and vertigo
Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. The choice of anti-emetic will depend… Aprepitant Betahistine Chlorpromazine Cinnarizine Cyclizine Domperidone Doxycycline Doxylamine + Pyridoxine Fosaprepitant Gastrointestinal disorders Hyoscine hydrobromide Mental health and illness Metoclopramide Nabilone Netupitant + Palonosetron Obstetrics and gynaecology Ondansetron Paediatrics and neonates Palonosetron Perphenazine Prochlorperazine Promethazine hydrochloride Promethazine teoclate Safety in Breastfeeding Trifluoperazine
22 May 2020
What is serotonin syndrome and which medicines cause it?
This Medicines Q&A outlines the causes and symptoms of serotonin syndrome and provides examples of medicines with the potential to cause serotonin syndrome. Adverse effects Almotriptan Amitriptyline Bupropion Buspirone Carbamazepine Chlorphenamine Citalopram Clomipramine Community Health Services Dextromethorphan Dosulepin Doxepin Duloxetine Eletriptan Ergotamine Escitalopram Fentanyl Fluoxetine Fluvoxamine Frovatriptan Granisetron Imipramine Interactions Isocarboxazid Levodopa Linezolid Lithium Lofepramine Mental Health Mental health and illness Methadone Methylthioninium chloride Metoclopramide Mirtazapine Moclobemide Naratriptan Nortriptyline Ondansetron Oxitriptan Oxycodone Paroxetine Pentazocine Pethidine Phenelzine Procarbazine Rasagiline Rizatriptan Selegiline Sertraline St. John's wort Sumatriptan Tapentadol Tramadol Tranylcypromine Trazodone Trimipramine Tryptophan Venlafaxine Zolmitriptan
27 November 2019
How can nausea and vomiting be treated during pregnancy?
This Medicines Q&A evaluates the published information available on the safety of the treatment options for nausea and vomiting in pregnancy. It includes information on… Cyclizine Domperidone Doxylamine + Pyridoxine Gastrointestinal disorders Ginger Metoclopramide Obstetrics and gynaecology Ondansetron Prochlorperazine Promethazine hydrochloride Promethazine teoclate Pyridoxine
18 October 2018
How should medicines be dosed in children who are obese?
Obesity results in physiological changes that can affect the volume of distribution and the clearance of drugs. The extent of these changes is variable and… Aciclovir Aminophylline Benzylpenicillin Carbamazepine Clindamycin Dosing Enoxaparin Esomeprazole Gentamicin Heparin Ibuprofen Metronidazole Morphine Omeprazole Ondansetron Paediatrics and neonates Paracetamol Phenobarbital Phenobarbital sodium Phenoxymethylpenicillin Phenytoin Phenytoin sodium Prednisolone Ranitidine Theophylline Tobramycin VancomycinMedicine Compliance Aid Stability
ZofranGlaxoSmithKline UK
GlaxoSmithKline UK
Zofran
Tablets f/c 4mg, 8mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Protect from light
Protect from light and store in airtight containers.
21 January 2015
Zofran MeltGlaxoSmithKline UK
GlaxoSmithKline UK
Zofran Melt
Oral lyophilisates 4mg, 8mg
R2 · Red 2Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Tablet designed to dissolve on tongue - unsuitable for MCA
21 January 2015
Lactation Safety Information
Alternative anti-emetic if appropriate
5HT3-receptor antagonist
No published evidence of safety
Used in infants > 1 month
15 July 2019
New Medicines
BekindaGastroenteritis-associated nausea
Information
Bekinda
New formulation
RedHill Biopharma
RedHill Biopharma
Development and Regulatory status
Phase III Clinical Trials
Phase III Clinical Trials
Phase III Clinical Trials
Category
5-HT3 antagonist - extended-release, once-daily formulation
About 20% of the UK population develop infectious intestinal disease each year. Viral infections cause 30 to 40% of gastroenteritis cases in industrialised countries. The figure is higher for children. Norovirus is the most common cause of viral infectious gastroenteritis in adults in England and Wales. Adenovirus and rotavirus are much less common in teenagers than in younger children [3].
Gastroenteritis-associated nausea
Oral