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What are the equivalent doses of oral morphine to other oral opioids when used as analgesics in adult palliative care?

9 November 2020Morphine is generally the strong opioid of choice for treating moderate to severe cancer pain and a common question is how to convert a dose…

Safety in Lactation: Opioid analgesics

21 October 2020The evidence relating to the safe use of opioid analgesics in breastfeeding mothers is very variable between individual drugs. This group of drugs presents a…

What is serotonin syndrome and which medicines cause it?

22 May 2020This Medicines Q&A outlines the causes and symptoms of serotonin syndrome and provides examples of medicines with the potential to cause serotonin syndrome.  

Can opioids be used for pain relief during pregnancy?

7 May 2020There are no specific guidelines for the treatment of pain in pregnancy. Not all analgesics are suitable for use during or at certain stages of…

What naloxone doses should be used in adults to urgently reverse the effects of opioids?

19 December 2019The opioid antagonist, naloxone, is a highly effective antidote the use of which is potentially life-saving. The drug has a role in a wide range…
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Medicine Compliance Aid Stability

OxyNormNapp Pharmaceuticals Ltd

Napp Pharmaceuticals Ltd
OxyNorm
Capsules - various strengths
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Airtight container.
11 May 2015

OxycontinNapp Pharmaceuticals Ltd

Napp Pharmaceuticals Ltd
Oxycontin
Tablets f/c, m/r various strengths
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Airtight container.
11 May 2015

TarginactNapp Pharmaceuticals Ltd

Napp Pharmaceuticals Ltd
Targinact
Tablets f/c, m/r - various strengths
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Protect from light
Airtight container and protect from light
11 May 2015

Lactation Safety Information

Oral / Parenteral

Oral / Parenteral
Dihydrocodeine, Morphine or other appropriate analgesic
Includes combinations with naloxone
Dose-dependent sedation has occurred in breastfed infants
Doses greater than 40mg/day should be avoided in breast feeding mothers
Oxycodone elimination in young infants is both variable and decreased
Avoid in neonates and monitor young infants (see summary)
29 July 2020