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Articles

Choosing a suitable antidepressant for people with coronary heart disease (CHD)

2 July 2021Prescribers may need to choose a safe antidepressant in people with CHD. We guide on available options. We do not cover management of complex depression.

Selective serotonin reuptake inhibitor (SSRI) formulations suggested for adults with swallowing difficulties

1 July 2021A range of selective serotonin reuptake inhibitors (SSRIs) are suitable for adults with swallowing difficulties.

Safety in Lactation: Antidepressants

21 October 2020Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Monamine-oxidase inhibitors (MAOIs) Due to the…

What is serotonin syndrome and which medicines cause it?

22 May 2020This Medicines Q&A outlines the causes and symptoms of serotonin syndrome and provides examples of medicines with the potential to cause serotonin syndrome.  

How do you switch between tricyclic, SSRI and related antidepressants?

21 October 2019This updated Medicines Q&A provides advice on the risks and suggested strategies for switching between tricyclic (TCA), selective serotonin reuptake inhibitors (SSRI) and related antidepressants.…
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Medicine Compliance Aid Stability

SeroxatGlaxoSmithKline UK

GlaxoSmithKline UK
Seroxat
Tablets 10mg, 20mg, 30mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Protect from light
Protect from moisture
Protect from light. Maximum of 7 days in a MCA. Protect from moisture.
26 October 2015

genericSandoz Ltd

Sandoz Ltd
generic
Tablets 10mg, 20mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Protect from light
Protect from moisture
Protect from light. Maximum of 7 days in a MCA. Protect from moisture.
26 October 2015

Lactation Safety Information

Yes
Sertraline
Significant published evidence of safety in breastfeeding
Long half-life increases risk of accumulation in breastfed infants. However., only small amounts have been detected in breast milk
Occasional adverse effects reported including irritability, restlessness, poor feeding, sedation and constipation
Monitor infant for colic, drowsiness, poor feeding and restlessness
22 January 2020