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Safety in Lactation: Metabolic disorders

18 September 2020These drugs are used for a variety of metabolic conditions, most of which are rare, and therefore give very limited opportunity to assess their impact…
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Medicine Compliance Aid Stability

DistamineAlliance Pharmaceuticals

Alliance Pharmaceuticals
Distamine
Tablets 125mg, 250mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Store in airtight containers.
11 February 2015

genericKent Pharmaceuticals Ltd

Kent Pharmaceuticals Ltd
generic
Tablets 125mg, 250mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Store in airtight containers.
11 February 2015

Lactation Safety Information

For Wilson's disease/ cystinuria/ autoimmune hepatitis

For Wilson's disease/ cystinuria/ autoimmune hepatitis
Trientine for Wilson's disease
Very limited published evidence of safety. Additional anecdotal evidence of safety indicates no effects in breastfed infants
Reduces copper and zinc levels in milk but there is no evidence this has a negative impact in the breastfed infant
Exposure of infant can be minimised by avoiding breastfeeding for 6 hours after a maternal dose
Monitor infant for signs of thrombocytopenia
22 January 2020

For rheumatoid arthritis

For rheumatoid arthritis
See summary
Very limited published evidence of safety. Additional anecdotal evidence of safety indicates no effects in breastfed infants
Reduces copper and zinc levels in milk but there is no evidence this has a negative impact in the breastfed infant
Exposure of infant can be minimised by avoiding breastfeeding for 6 hours after a maternal dose
Monitor infant for signs of thrombocytopenia
22 January 2020