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How should medicines be dosed in children who are obese?

28 May 2021Review on how to calculate medicine doses in children who are obese which includes a table on commonly prescribed medicines.

Safety in Lactation: Drugs used in status epilepticus

5 November 2020Choice of treatment will be influenced by the clinical situation. The evidence for these drugs in breastfeeding is based on their longer-term use rather than…
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Lactation Safety Information

Parenteral for status epilepticus

Parenteral
for status epilepticus
Phenytoin if appropriate
Moderate level of published evidence of use in breastfeeding
Used in full-term neonates from birth
Very long half-life increases the risk of accumulation in breastfed infants
Significant amounts in breast milk; in general the infant will receive 30% of mother’s dose
Case reports of sedation in breastfed infants; other concomitant drugs may have been involved in some cases
10 August 2020