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Safety in Lactation: Corticosteroids

9 November 2020There is very limited information on the use of corticosteroids during breastfeeding, although they are likely to be present in milk. Avoid prolonged high dose…

Safety in lactation: Drugs for chronic bowel disorders

21 September 2020Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Aminosalicylates for chronic bowel disorders Mesalazine…

Safety in Lactation: Drugs for otitis externa

17 September 2020Preparations for treating otitis externa have limited systemic absorption in the mother, and pose negligible risk to a breastfed infant. There is no published evidence…

What is the equivalent dose of oral prednisolone to intravenous (IV) hydrocortisone?

29 May 2020Prednisolone 5mg orally is equivalent to hydrocortisone 20mg intravenously (equivalent anti-inflammatory dose). The peri-operative dose of hydrocortisone required may be higher than the equivalent prednisolone…

How should medicines be dosed in children who are obese?

18 October 2018Review on how to calculate medicine doses in children who are obese which includes a table on commonly prescribed medicines.
Search Articles

Medicine Compliance Aid Stability

genericZentiva

Zentiva
generic
Tablets 25mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Protect from light
Protect from moisture
Protect from light. Protect from moisture. Store in airtight containers. Hygroscopic. Due to the hygroscopic nature of the tablets, maximum 8 day expiry in a MCA.
12 February 2015

genericActavis UK Ltd

Actavis UK Ltd
generic
Tablets 1mg, 5mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Protect from light
Protect from moisture
Protect from light. Protect from moisture. Store in airtight containers. Hygroscopic. Due to the hygroscopic nature of the tablets, maximum 8 day expiry in a MCA.
12 February 2015

DeltacortrilAlliance Pharmaceuticals

Alliance Pharmaceuticals
Deltacortril
Tablets e/c 2.5mg, 5mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Protect from light
Protect from moisture
Protect from light. Protect from moisture. Store in airtight containers. Hygroscopic. Due to the hygroscopic nature of the tablets, maximum 8 day expiry in a MCA.
12 February 2015

Lactation Safety Information

systemic corticosteroid/immunosuppressant

systemic corticosteroid/immunosuppressant
Yes
Limited published evidence of safety although extensive experience of safe use in breastfeeding
Small amounts in breast milk
Doses up to 40mg daily unlikely to cause adverse effects in the infant
29 January 2021

Local injection

Local injection
Yes
24 September 2020

In the ear

In the ear
Yes
24 September 2020

Oral / rectal for inflammatory bowel disease

Oral / rectal
for inflammatory bowel disease
Yes
-
Limited published evidence of safety although extensive experience of safe use in breastfeeding
Small amounts in breast milk after oral administration
Doses up to 40mg orally daily unlikely to cause adverse effects in the infant
3 February 2021