Pregabalin
Articles · Medicine Compliance Aid Stability · Lactation Safety Information · New Medicines · Published , updated
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Articles
16th April 2018
Gabapentin and pregabalin—are they safe whilst breastfeeding?
This UKMi Medicines Q & A reviews the evidence available, and makes recommendations, for the use of gabapentin and pregabalin during breastfeeding. Summary: Limited data… Gabapentin Obstetrics and gynaecology Paediatric and neonatal medicine Pregabalin Q&A Safety in Lactation
6th July 2016
Pregabalin pain patent: legal case summary
This report summarises the Court of Appeal judgement on the patent infringement case between Pfizer (as Warner-Lambert), and Actavis and Mylan, and the implication of… Acute Care Mental Health Pregabalin Primary Care
30th March 2015
How do you switch between pregabalin and gabapentin for neuropathic pain, and vice versa?
This recently updated Medicines Q&A evaluates the limited published evidence available on managing a switch between pregabalin and gabapentin for neuropathic pain, and vice versa. Anaesthesia and pain Gabapentin Pregabalin Q&A
17th December 2014
Can antiepileptics (anticonvulsants) increase the risk of osteoporosis?
This updated Medicines Q&A evaluates the evidence available on the risk of osteoporosis in patients with epilepsy taking antiepileptic drugs. Carbamazepine Clobazam Eslicarbazepine Ethosuximide Fosphenytoin Gabapentin Lacosamide Lamotrigine Levetiracetam Musculo-skeletal disorders Oxcarbazepine Perampanel Phenobarbital Phenobarbital sodium Phenytoin Phenytoin sodium Pregabalin Primidone Q&A Retigabine Rufinamide Sodium valproate Tiagabine Topiramate Valproic acid Vigabatrin Zonisamide
23rd July 2014
What non-hormonal alternatives to antidepressants are available for the management of menopausal hot flushes?
This is one of two Medicines Q&As addressing the management of menopausal hot flushes with non-hormonal drug therapy. Summary Hot flushes (or flashes), along with… Clonidine Gabapentin Methyldopa Obstetrics and gynaecology Octreotide Pregabalin Q&A
3rd July 2013
Gabapentin and Pregabalin Offender Health Audit Report and Audit Tool
This report and associated survey and audit tool describe the process and outcomes of an England-wide collaborative audit and survey of the use of gabapentin… Gabapentin Health and Justice Implementation Pregabalin Research and Audits
20th May 2012
Safety in Lactation: Control of epilepsy
Choice will depend on clinical condition, and should primarily be based on suitability for the patient, rather than safety during breastfeeding. Whilst sodium valproate is… Carbamazepine Clobazam Clonazepam Eslicarbazepine Ethosuximide Gabapentin Lacosamide Lamotrigine Levetiracetam Oxcarbazepine Perampanel Phenobarbital Phenytoin Pregabalin Primidone Retigabine Rufinamide Sodium valproate Tiagabine Topiramate Vigabatrin ZonisamideMedicine Compliance Aid Stability
Lyrica · Pfizer Ltd
Pfizer Ltd
Lyrica
Capsules 25mg, 50mg, 75mg, 100mg, 150mg, 225mg, 300mg,
A2 · Amber 2 · No stability data is available, the manufacturer does not, or cannot recommend use in CAs but there are no theoretical concerns with the product.
No special precautions for storage
No special requirements for storage.
9th February 2015
Lactation Safety Information
For epilepsy
For epilepsy
Gabapentin
No adverse effects reported in breastfed infants
Very limited published evidence of safety
Single case report of low serum levels in breastfed infant
17th April 2018
New Medicines
Lyrica · Partial onset seizures in children aged 4 to 16 years - adjunctive therapy
Information
Lyrica
Licence extension / variation
Pfizer
Pfizer
Development and Regulatory status
Phase III Clinical Trials
Phase III Clinical Trials
Phase III Clinical Trials
2020
Category
GABA receptor agonist
Epilepsy is about twice as common in children as in adults (about 700 per 100,000 in children under the age of 16 years compared to 330 per 100,000 in adults) [2].
Partial onset seizures in children aged 4 to 16 years - adjunctive therapy
Oral