dm+d

Unassigned

New Medicines

Amyotrophic lateral sclerosis (motor neurone disease)

Information

New molecular entity
Cytokinetics
Cytokinetics

Development and Regulatory status

None
None
Phase III Clinical Trials
Yes
Yes

Category

Fast skeletal muscle troponin activator (FSTA) - slows rate of calcium release from the regulatory troponin complex of fast skeletal muscle fibers, leading to increased skeletal muscle contractility.
MND is mostly a sporadic disease of middle and elderly life presenting in the sixth and seventh decades. The incidence is 2-4 per 100,000 per annum, with onset typically in the sixth and seventh decades. The male to female ratio is 2:1 [5].
Amyotrophic lateral sclerosis (motor neurone disease)
Oral