dm+d
Unassigned
New Medicines
Amyotrophic lateral sclerosis (motor neurone disease)
Information
New molecular entity
Cytokinetics
Cytokinetics
Development and Regulatory status
None
None
Phase III Clinical Trials
Yes
Yes
Category
Fast skeletal muscle troponin activator (FSTA) - slows rate of calcium release from the regulatory troponin complex of fast skeletal muscle fibers, leading to increased skeletal muscle contractility.
MND is mostly a sporadic disease of middle and elderly life presenting in the sixth and seventh decades. The incidence is 2-4 per 100,000 per annum, with onset typically in the sixth and seventh decades. The male to female ratio is 2:1 [5].
Amyotrophic lateral sclerosis (motor neurone disease)
Oral