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Articles
Safety in Lactation: Antipsychotics
22 September 2020Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Oral and non-depot antipsychotics with less…
Refrigerated Storage
Risperdal ConstaJanssen-Cilag Ltd
Janssen-Cilag Ltd
Risperdal Consta
25mg/ 37.5mg / 50 mg powder and solvent for prolonged-release suspension for intramuscular injection
In the event of an inadvertent temperature excursion the following data may be used:
If refrigeration is unavailable, Risperdal Consta can be stored at temperatures not exceeding 25°C for no more than 7 days prior to administration.
Please also refer to the manufacturer’s product literature for recommended storage information at https://www.medicines.org.uk
Contact Janssen-Cilag Ltd in cases where additional stability data is required. Refer to the current BNF for company contact details.
Yes - reduce to 7 days from date of excursion as above
29 October 2021
London MI Service
Lactation Safety Information
Oral
Oral
Quetiapine, Haloperidol
Limited evidence that maternal oral doses up to 6mg daily produce low levels in milk
Long half-life of active metabolite increases risk of accumulation in breastfed infants
Monitor infant for sedation, poor feeding, behavioural effects, extrapyramidal symptoms, and developmental milestones
22 January 2020
Depot injection
Depot injection
No published evidence of safety for use as depot injection. However maternal oral doses of up to 6mg daily produce low levels in milk
Long half-life of active metabolite increases risk of accumulation in breastfed infants
Monitor infant for sedation, poor feeding, behavioural effects, extrapyramidal symptoms, and developmental milestones
22 January 2020