Sarilumab

Refrigerated Storage · New Medicines ·
Unassigned

Refrigerated Storage

Kevzara · Sanofi Genzyme Therapeutics

Sanofi Genzyme Therapeutics
Kevzara
Solution for injection in pre-filled syringe pen, solution for injection in pre-filled syringe pen, 150mg and 200mg

Contact Genzyme in all cases where a deviation from the recommended storage conditions has occurred. Refer to the current BNF for company contact details.
Please also refer to the manufacturer’s product literature for recommended storage information at https://www.medicines.org.uk

Genzyme advise that individuals contact them each time for requests regarding extended stability of their products to ensure that the most current information is reflected and any individual specific stability questions can be addressed.

17th December 2019
London MI Service

New Medicines

Kevzara · Giant cell (temporal) arteritis

Information

Kevzara
Licence extension / variation
Genzyme Therapeutics
Sanofi

Development and Regulatory status

Discontinued
Discontinued
Discontinued
Jul 20 · Removed from company pipeline, and no longer in planned filings. Assume development discontinued [8].

Category

Fully human antibody to the interleukin-6 receptor (IL-6R)
GCA occurs in 2.2 per 10,000 patient years in the UK [1].
Giant cell (temporal) arteritis
Subcutaneous

Kevzara · Polymyalgia rheumatica

Information

Kevzara
Licence extension / variation
Genzyme Therapeutics
Sanofi

Development and Regulatory status

Discontinued
Discontinued
Discontinued
Jul 20 · Removed from Sanofi pipeline and no longer in planned filings. Assume development discontinued [5].

Category

Fully human antibody to the interleukin-6 receptor (IL-6R)
The annual incidence of the disease in the general population in the UK has been estimated as 84 per 100,000. PMR occurs almost exclusively in people aged above 50 and the mean age of onset is about 73 [1].
Polymyalgia rheumatica
Subcutaneous