Sodium valproate

Articles · Medicine Compliance Aid Stability · Lactation Safety Information ·

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Articles

Medicine Compliance Aid Stability

Epilim · Sanofi

Sanofi
Epilim
Tablets crushable 100mg
A3 · Amber 3 · No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Protect from moisture
Company info - if benefit outweighs risk, repackage weekly not monthly and protect from moisture and humidity.
2nd March 2015

Episenta · Desitin

Desitin
Episenta
Capsules m/r 150mg, 300mg
R2 · Red 2 · Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Unsuitable for MCA as preparations are hygroscopic which can affect release profile.
2nd March 2015

generic · Non-proprietary

Non-proprietary
generic
Tablets e/c 200mg, 500mg
R2 · Red 2 · Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Unsuitable for MCA as preparations are hygroscopic which can affect release profile.
2nd March 2015

generic · Non-proprietary

Non-proprietary
generic
Tablets crushable 100mg
R2 · Red 2 · Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Unsuitable for MCA as preparations are hygroscopic which can affect release profile.
2nd March 2015

Epilim Chrono · Sanofi

Sanofi
Epilim Chrono
Tablets m/r 200mg, 300mg, 500mg
A3 · Amber 3 · No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Protect from moisture
Company info - if benefit outweighs risk, repackage weekly not monthly and protect from moisture and humidity.
2nd March 2015

Epilim · Sanofi-Aventis

Sanofi-Aventis
Epilim
Tablets e/c 200mg, 500mg
A3 · Amber 3 · No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Unsuitable
Company info - if benefit outweighs risk, repackage weekly not monthly and protect from moisture and humidity.
2nd March 2015

Lactation Safety Information

For bipolar disorder

For bipolar disorder
Carbamazepine; Appropriate second generation antipsychotic
Significant published evidence of safety in breastfeeding indicates small amounts in breast milk
Monitor infant for jaundice, bruising, and bleeding
MHRA states that it should not used in women of child bearing age unless Pregnancy Prevention Programme is in place, and only if other treatments are ineffective or not tolerated. For this reason, carbamazepine is preferred first-line in breastfeeding (see summary)
22nd January 2020

Oral / parenteral for epilepsy

Oral / parenteral
for epilepsy
Suitable alternative antiepileptic
Significant published evidence of safety in breastfeeding indicates small amounts in breast milk
Monitor infant for jaundice, bruising, and bleeding
Used in full-term neonates from birth
MHRA states that it should not used in women of child bearing age unless Pregnancy Prevention Programme is in place, and only if other treatments are ineffective or not tolerated (see summary).
22nd January 2020