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Articles

Medicines that are considered safe for use in the acute porphyrias

29 May 2020The UK Porphyria Medicines Information Service (UKPMIS) and Cardiff Porphyria Service produce a list of medicines that are considered to be safe for use in…
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New Medicines

Information

Lokelma
Licence extension / variation
AstraZeneca
AstraZeneca

Development and Regulatory status

Phase III Clinical Trials
Phase III Clinical Trials
Phase III Clinical Trials

Category

A potassium binding modulator
In 2016, 6.5 million English adults had chronic kidney disease (CKD), of which 3 million had stage 3-5 disease [3]. It is well known that patients with CKD have a strong risk of cardiovascular disease (CVD). Impairment in renal function can increase the risk of CVD two- to fourfold [3,4].
Arrhythmia-related cardiovascular disorders in patients on chronic dialysis with recurrent hyperkalaemia
Oral