Teprasiran

Unassigned

New Medicines

Renal transplant, prevention of delayed graft function in recipients of a deceased older donor kidney

Information

New molecular entity
Not Known
Quark Pharmaceuticals

Development and Regulatory status

None
Phase III Clinical Trials
Phase III Clinical Trials

Category

Small interfering RNA (sIRNA) that temporarily and reversibly inhibits the activity of the p53 gene.
3,250 renal transplants were carried out in UK Apr13-Mar 14 (NHSBT). Values for rates of delayed graft function vary widely: in studies quoted by NICE, they ranged from 24% to 89% depending on donor type and technique used for storage [4].
Renal transplant, prevention of delayed graft function in recipients of a deceased older donor kidney
Intravenous