How should medicines be dosed in children who are obese?

28 May 2021Review on how to calculate medicine doses in children who are obese which includes a table on commonly prescribed medicines.

Safety in Lactation: Drugs for obstructive airways disease

25 September 2020Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Bronchodilators Most bronchodilators are considered to…

What are the clinically significant drug interactions with tobacco smoking?

23 March 2020This Medicines Q&A summarises those drug interactions with tobacco smoking that are considered to be most clinically important. Most interactions between drugs and tobacco smoking…

How is an intravenous aminophylline dose converted to an oral aminophylline or theophylline dose?

27 November 2019This updated Medicines Q&A explains how to convert an intravenous aminophylline dose to an oral aminophylline or theophylline dose and includes examples of conversion calculations
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Medicine Compliance Aid Stability

Slo-PhyllinMerck Serono

Merck Serono
Capsules m/r 60mg, 125mg, 250mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Protect from moisture
Need moisture proof conditions.
29 September 2015

Nuelin SAMeda Pharmaceuticals

Meda Pharmaceuticals
Nuelin SA
Tablets m/r 175mg, 250mg
R2 · Red 2Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Store in original packaging.
29 September 2015

Uniphylline ContinusNapp Pharmaceuticals Ltd

Napp Pharmaceuticals Ltd
Uniphylline Continus
Tablet m/r 200mg, 300mg, 400mg
A2 · Amber 2No stability data is available, the manufacturer does not, or cannot recommend use in CAs but there are no theoretical concerns with the product.
Protect from moisture
Need moisture proof conditions. Maximum 7 days in a MCA.
29 September 2015

Lactation Safety Information

Salbutamol/ Terbutaline
Xanthine bronchodilator
Limited published evidence of safety
Irritability and fretful sleep reported in one breastfed infant
Adverse effects potentially more likely in premature and newborn infants
Avoid feeding for 2 hours after IV dose and 4 hours after immediate-release oral preparation
Monitor infant for irritability
29 July 2020